Your Questions About Norovirus, Answered
Norovirus is the leading cause of vomiting and diarrhea from acute gastroenteritis in the United States and the leading cause of foodborne illness — an estimated 19–21 million US illnesses a year, per CDC. This site reads the primary sources behind the headlines: the CDC pages, the FDA Food Code, the challenge studies, and the monthly surveillance data — and says where the evidence is uncertain.
Latest Norovirus News
Last updated: September 20, 2026 · Checked for new stories September 30, 2026
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No early success for Moderna’s norovirus vaccine in phase 3 trial
The vaccine maker said its investigational mRNA norovirus vaccine did not meet statistical criteria for early success.
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The Eaton wildfire evacuation shelter near LA saw outbreaks of norovirus, COVID, and flu, report reveals
The study highlights how shelters can experience infectious disease outbreaks and how they can be prevented.
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Quick takes: Fatal H5N6 avian flu case, cruise ship norovirus outbreak, dermatophilosis in MSM
The dermatophilosis rash has caused only mild cases in men who have sex with men in Europe.
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Quick takes: Clade 1 mpox in NYC, cruise ship norovirus outbreak, avian flu case in Cambodia
Cambodia has reported 36 human H5 infections since 2023.
What Is Norovirus?
Norovirus is a highly contagious RNA virus and the most common cause of acute gastroenteritis — illness characterized by nausea, vomiting, diarrhea, and stomach cramping — in people of all ages worldwide. The virus belongs to the family Caliciviridae and includes multiple genetically distinct genogroups; per CDC, GII.4 viruses have caused the majority of outbreaks worldwide since 2002, with GII.17 displacing them in the US for one season in 2024–2025.
According to the CDC's Facts and Stats page, norovirus causes on average 19–21 million illnesses, 2.27 million outpatient visits, 465,000 emergency department visits, 109,000 hospitalizations, and 900 deaths in the United States each year. Globally, it accounts for roughly 685 million cases and 50,000 child deaths annually, mostly in developing countries (CDC).
The virus is extraordinarily infectious. The often-quoted "18 viral particles" is a 2008 modeling estimate; a 2014 human-challenge trial measured the 50% infectious dose at about 1,300 — and either number is invisible. Norovirus persists on surfaces "for days or weeks" and "is resistant to many common disinfectants" (CDC), making it a persistent challenge in healthcare facilities, schools, cruise ships, and food-service environments.
There is no approved vaccine and no specific antiviral treatment as of September 2026. Management is supportive: oral rehydration to prevent dehydration, rest, and strict hygiene to prevent spread.
Key Facts
- Most illnesses last 1–3 days in otherwise healthy adults
- Most people recover fully without medical intervention
- Vulnerable groups (elderly, immunocompromised, young children) face higher risk of severe dehydration
- Outbreaks peak in fall and winter — norovirus is sometimes called the "winter vomiting bug"
How Norovirus Spreads
The CDC's one-sentence version: you get norovirus "by accidentally getting tiny particles of feces (poop) or vomit in your mouth from a person infected with norovirus." That happens through direct contact with a sick person, contaminated food (an infected worker's bare hands, or oysters from sewage-tainted water), contaminated water, and contaminated surfaces touched and then carried to the mouth. Vomiting adds a fifth path: the CDC lists "tiny drops of vomit … spray through the air, landing on surfaces or entering another person's mouth," and a 2000 outbreak investigation found that the share of diners who fell ill dropped with distance from the one person who vomited.
How much virus it takes
Two peer-reviewed human-challenge studies disagree by almost 100×: a 2008 model put the median infectious dose at ~18 particles; a 2014 trial measured ~1,300. Both are small. We publish both, with DOIs, and explain why they differ.
How long people stay contagious
CDC: "2 weeks or more after you feel better." In the challenge study behind that line, shedding began 18 hours after infection — before symptoms — and lasted a median of 28 days, peaking at 95 billion genome copies per gram of stool.
Who cannot catch it
About 29% of volunteers in a 2003 challenge study carried a FUT2 gene variant that made them fully resistant to the strain tested, at any dose. CDC: your risk is "determined in part by your genes."
Symptoms and When to Seek Care
Symptoms begin 12 to 48 hours after exposure and are sudden: diarrhea, vomiting, nausea, and stomach pain are the most common, with fever, headache, and body aches as "other symptoms" (CDC). Most people are better in 1 to 3 days. Roughly one in three infected adults in challenge studies never developed symptoms at all — but shed virus regardless.
The complication is dehydration. The CDC's warning signs are decreased urination, dry mouth and throat, feeling dizzy when standing, and — in children — crying with few or no tears and unusual sleepiness or fussiness. Severe dehydration "may require hospitalization for treatment with fluids given through your vein."
The age pattern is the most useful fact on the Symptoms page: the emergency-department visits are "mostly in young children," while the deaths are "mostly among adults aged 65 and older" (CDC). By age five, one child in 40 will have had an ED visit for norovirus and one in 160 a hospitalization.
Prevention: What Works and What Doesn't
What works (CDC)
- Soap and water for at least 20 seconds — "hand sanitizer alone does not work well against norovirus"
- Chlorine bleach at 1,000–5,000 ppm (5–25 tablespoons of 5–8% household bleach per gallon of water), left on the surface at least 5 minutes, or an EPA-registered product with a norovirus claim
- Cooking shellfish to an internal temperature of at least 145°F — "quick steaming processes will not heat foods enough"
- Staying home for at least 48 hours after symptoms stop before preparing food or caring for others
- Hot-water laundry at the maximum cycle length, dried on high heat, handled without shaking
What doesn't
- Alcohol hand sanitizer on its own — norovirus has no lipid envelope for alcohol to disrupt
- Quaternary-ammonium ("quat") disinfectants without bleach or an EPA norovirus registration
- Vinegar-based cleaners
- Freezing — the virus survives it
- Light steaming of oysters
- Antibiotics — "they fight bacteria, not viruses" (CDC)
For food workers the rules carry legal weight: under the FDA Food Code 2022, an employee diagnosed with norovirus must be excluded from the establishment and cannot be reinstated until more than 48 symptom-free hours have passed and the local regulatory authority approves. The Food Safety page quotes the sections.
Treatment
Care is supportive, and for most people that means fluids at home. The CDC's advice: "oral rehydration fluids that you can get over the counter are most helpful for mild dehydration"; sports drinks and other caffeine-free, alcohol-free drinks "can help" but "may not replace important nutrients and minerals." WHO describes oral rehydration solution as "a mixture of clean water, salt and sugar" that "costs a few cents per treatment." Severe dehydration means IV fluids in hospital.
What "supportive care" adds up to across a US year, per CDC: about 2.27 million outpatient visits, 465,000 emergency-department visits, and 109,000 hospitalizations — nearly all of the last for dehydration. Set against 19–21 million illnesses, roughly six in seven are managed at home without a clinician. No antiviral is approved; the most advanced vaccine candidate is in a Phase 3 trial of nearly 38,000 adults with results expected in 2027.
This Season, From CDC's Live Surveillance
| Season (Sep–Aug) | Outbreaks reported by NoroSTAT states (Aug–Jul) | Leading genotype (CaliciNet) |
|---|---|---|
| 2024–2025 | 2,650 — above the 2012–2025 interquartile range | GII.17[P17], 306 of 411 typed outbreaks (74%) |
| 2025–2026 | 1,392 — "within the middle 50%" of prior seasons | GII.4 Sydney[P16], 73 of 153 (48%); GII.17 second at 18% |
Sources: CDC NoroSTAT Data (updated August 26, 2026) and CaliciNet Data (updated September 3, 2026). Percentages are our arithmetic from CDC's counts.
The 2024–2025 season was the first since 2012 in which GII.4 Sydney was not the leading US strain, and the NoroSTAT states recorded nearly twice as many outbreaks as in the following, normal season — consistent with the CDC's observation that "in years when there is a new strain of the virus, there can be 50% more norovirus illness." The Outbreaks page carries the full tables, the cruise-ship outbreak counts from CDC's Vessel Sanitation Program (14, 18, 23, and 9 posted outbreaks in 2023, 2024, 2025, and 2026 to July), and the settings where outbreaks concentrate — over half of them in long-term care facilities, per CDC, and only about 1% on cruise ships.
Where the Numbers Come From — and What Isn't Known
None of the US figures on this page is a count. Norovirus is not individually reportable — CDC's reporting page states that health departments "are not required to report individual cases of norovirus illness to CDC," and most clinics do not test for it. The 19–21 million illnesses trace to Hall et al. (2013); the 109,000 hospitalizations, 465,000 ED visits, and 900 deaths to Burke et al. (2021), whose confidence intervals — 80,000–145,000 hospitalizations, 650–1,100 deaths — the CDC page leaves out. The 685 million global illnesses is a model with an uncertainty range of 491 million to 1.1 billion.
That is why this site does not publish a norovirus case-fatality rate or hospitalization rate: dividing one modeled estimate by another produces a decimal that looks precise and is not. The Norovirus Risk Perspective page shows each figure beside its source and date, leaves those two cells blank with the reason, and links to the hub's Virus Risk Perspective, where norovirus — the highest-incidence, among the lowest-lethality viruses in the set — is compared with 14 others on the same five measures.
When this site gets something wrong, or is told it has and turns out not to have, the corrections page records it: what was published, what it says now, and the source that settled it.
All Norovirus Topics
Symptoms
Nausea, vomiting, diarrhea, cramping — what to expect and when to seek care
Transmission
How norovirus spreads — person-to-person, contaminated food, surfaces, and water
Prevention
Handwashing technique, surface disinfection, food handling, and isolation protocols
Treatment
Oral rehydration, symptom management, and when hospitalization is needed
Outbreaks
U.S. and global outbreak data, high-risk settings, and historical major events
FAQ
Answers to the most common questions about norovirus, from contagious period to reinfection
Preparedness Kit
Recommended products for managing norovirus at home — ORS, disinfectants, and more
Rental Host Cleanup
A guest was sick in your Airbnb or rental — the CDC protocol as a whole-unit turnover
Norovirus on Cruise Ships
Why cruise ships are high-risk environments and how to protect yourself while traveling
School & Daycare Rules
When a child can go back — the 24-hour rule, the 48-hour rule, and who each applies to
Food-Handler Exam Rules
The sick-worker rules the food handler and manager exams test — explained from the Food Code, with 80 practice questions
Norovirus vs Rotavirus vs Food Poisoning
One table: hours to onset, duration, who, season, and what each diagnosis changes about what you do
What an Outbreak Costs
Restaurant, cruise ship, nursing home, hospital, school — per outbreak, derived from public figures with the arithmetic shown
Immunity & Reinfection
Why you can get it twice — how long protection lasts, why it is strain-specific, and the one in five who are resistant
Food Safety
Safe food handling, cooking temperatures, and which foods carry the highest risk
Risk Perspective
How norovirus compares to 14 other viruses on exposure, hospitalization, and death
Latest Norovirus Research
- Latest
Bile and capsid variation coregulate histo-blood group antigen recognition and serum neutralization potency in GII.12 human norovirus
- Environmental research
Sphingobacterium-mediated EPS shielding exacerbates norovirus environmental persistence and risk in swine farms
- International journal of food microbiology
Systematic evaluation of the micro-volume PEG-enrichment pretreatment for norovirus detection across seven commercially available bivalve species
- The Journal of infectious diseases
Impact of dose on norovirus antibody kinetics following infection or vaccination
- bioRxiv : the preprint server for biology
Plscr1 inhibits murine norovirus entry
Sources & References
- Centers for Disease Control and Prevention (CDC). Norovirus Facts and Stats. cdc.gov/norovirus/data-research (updated May 8, 2024).
- Centers for Disease Control and Prevention (CDC). About Norovirus. cdc.gov/norovirus/about.
- Centers for Disease Control and Prevention (CDC). How to Prevent Norovirus. cdc.gov/norovirus/prevention.
- World Health Organization (WHO). Diarrhoeal Disease Fact Sheet. who.int/news-room/fact-sheets/detail/diarrhoeal-disease (March 7, 2024).
- Centers for Disease Control and Prevention (CDC). How Norovirus Spreads. cdc.gov/norovirus/causes; Norovirus Outbreaks. cdc.gov/norovirus/outbreak-basics; Norovirus Reporting and Surveillance. cdc.gov/norovirus/php/reporting.
- Centers for Disease Control and Prevention (CDC). NoroSTAT Data (August 26, 2026) cdc.gov/norovirus/php/reporting/norostat-data; CaliciNet Data (September 3, 2026) cdc.gov/norovirus/php/reporting/calicinet-data.
- U.S. Food and Drug Administration. Food Code 2022, §§ 2-201.11–2-201.13. fda.gov/food/fda-food-code/food-code-2022.
- Teunis PFM, et al. Norwalk virus: how infectious is it? J Med Virol. 2008;80(8):1468–1476. DOI: 10.1002/jmv.21237. Atmar RL, et al. Determination of the 50% human infectious dose for Norwalk virus. J Infect Dis. 2014;209(7):1016–1022. DOI: 10.1093/infdis/jit620. Atmar RL, et al. Norwalk virus shedding after experimental human infection. Emerg Infect Dis. 2008;14(10):1553–1557. DOI: 10.3201/eid1410.080117. Lindesmith L, et al. Human susceptibility and resistance to Norwalk virus infection. Nat Med. 2003;9(5):548–553. DOI: 10.1038/nm860. Marks PJ, et al. Evidence for airborne transmission of Norwalk-like virus (NLV) in a hotel restaurant. Epidemiol Infect. 2000;124(3):481–487. DOI: 10.1017/S0950268899003805.
- Hall AJ, et al. Norovirus disease in the United States. Emerg Infect Dis. 2013;19(8):1198–1205. PubMed 23876403. Burke RM, et al. Burden of norovirus in the United States, as estimated based on administrative data, 2001–2015. Clin Infect Dis. 2021;73(1):e1–e8. DOI: 10.1093/cid/ciaa438. Bartsch SM, et al. Global economic burden of norovirus gastroenteritis. PLOS ONE. 2016;11(4):e0151219. DOI: 10.1371/journal.pone.0151219.